Team

Scientific and clinical experience in ocular gene therapy.

Visiogene is a small preclinical-stage company built around retinal delivery science, AAV vector development, retinal disease models, and clinical research perspective.

Founder and CEO

Rajendra Kumar‑Singh, PhD

Dr. Kumar‑Singh is Professor of Developmental, Molecular and Chemical Biology at Tufts University School of Medicine in Boston, Massachusetts.

Previously, he was Scientific Founder and Chief Scientific Officer of Hemera Biosciences and inventor of soluble sCD59 (HMR59) for dry age‑related macular degeneration, also known as geographic atrophy. HMR59 was acquired by Janssen Pharmaceuticals and is now known as JNJ‑81201887.

He completed his PhD at the University of Dublin, Trinity College, in ocular genetics, followed by postdoctoral work at the University of Michigan, Ann Arbor, faculty roles at UCLA School of Medicine and the University of Utah, and progression to tenured Professor at Tufts University School of Medicine.

Senior Scientist

Manish Mishra, PhD

Dr. Mishra has experience in animal models of retinal degeneration and development and use of recombinant AAV vectors for retinal gene therapy.

He graduated from the CSIR‑Indian Institute of Toxicology Research in India and was a Research Associate at Wayne State University School of Medicine before moving to Tufts University as a Research Associate. He later worked in industry as a key member of the CNS and ocular gene therapy program at PTC Therapeutics and has authored more than 40 peer‑reviewed publications.

Clinical and Research Advisor

Tiffany Kolniak, MD, PhD

Dr. Kolniak obtained her PhD in Neuroscience from the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo.

She has published in molecular therapies for retinal degeneration, with a focus on knockdown strategies for autosomal dominant retinal diseases. Dr. Kolniak obtained her medical degree from the University at Buffalo, completed residency at Mount Auburn Hospital, joined Tufts Medical Center as a primary care physician, and is currently a primary care physician at Newton‑Wellesley Hospital.

Company foundation

The team structure reflects the scientific work.

Visiogene’s work requires vector design, ocular disease models, protein and gene delivery methods, and clinically informed selection of disease settings where local ocular treatment can be studied rigorously.

Ocular genetics

Retinal disease mechanisms

Experience in inherited and acquired retinal disease informs target and indication selection.

AAV development

Vector engineering

Preclinical work is centered on delivery technology, payload design, and disease model testing.

Clinical perspective

Translation context

Clinical and research advisory input helps keep program selection connected to patient-relevant ocular disease.